The match kicks off at 15:00. Meanwhile, Burkina Faso will face Cape Verde in the other Group D match.
The last time South Africa played Senegal was in the 2015 edition of the annual Nelson Mandela Challenge where the home team won 1-0 at Orlando Stadium.
Coach Shakes “Mshege” Mashaba assured the South African public that he was intent on making the country proud by winning Senegal.
“We must win at all cost. No draws or lose. The boys are aware that its all or nothing.”
Meanwhile, new Bafana Bafana striker Lars Veldwijk says he looks forward wearing the Bafana jersey and making use of it, if he gets capped.
The imposing striker said he was excited to represent Bafana Bafana and says his dream was to go to the 2018 World Cup in Russia.